Causes of diseases of the cardiovascular System

Causes of diseases of the cardiovascular systemDiseases of the cardiovascular system are among the most common causes of death worldwide. Their origin is often multifactorial and results from the complex Interplay of genetic, environmental and behavioural factors. In the Following, the main causes are presented in a systematic way.1. Modifiable Risk FactorsOf the modifiable risk factors that have a significant impact on the development of cardiovascular diseases, include:The use of tobacco. Smoking cigarettes leads to damage of the blood vessel inner wall (endothelium), promotes atherosclerosis and increases the risk for heart attacks and stroke significantly.An Unbalanced Diet. A diet with a high content of saturated fatty acids, TRANS-fats, salt and sugar increases the level of cholesterol (especially LDL cholesterol), promotes the development of hypertension and obesity.A lack of exercise. A low physical activity level is associated with an increased risk for obesity, type 2 Diabetes mellitus and arterial hypertension. Regular physical activity strengthens the cardiovascular System and lowers the overall risk.Overweight and obesity. A higher percentage of body fat, especially visceral fat, is associated with a chronic inflammatory response and promotes insulin resistance, hypertension, dyslipidemia and the risk of coronary heart disease (CHD).Hypertension. A permanently elevated blood pressure (≥ 140/90 mmHg) charged to vessels of the heart and the blood, accelerates the atherosclerosis development and is a major risk factor for heart attack, heart failure, and stroke.Dyslipidemia. An unfavorable lipid profile with elevated LDL cholesterol, low HDL cholesterol and elevated triglycerides favors the formation of hardening of the arteries (atherosclerosis).Diabetes mellitus type 2. The chronically elevated blood glucose concentration causes damage to the blood vessels and increases the risk for cardiovascular events in the two-to three-fold.Stress and psychosocial factors. Chronic Stress, Depression, and social Isolation can increase the neuro-endocrine mechanisms (e.g., increased Catecholamine release), the cardiovascular risk.2. Non-modifiable risk factorsSome risk factors you can't control, but must be considered in the risk assessment shall take account of:Genetic Disposition. Familial clustering of cardiovascular disease (e.g., earlier myocardial infarction in first-degree Relatives) suggest a genetic predisposition. Single-gene disorders such as familial hypercholesterolemia are rare, but of high clinical relevance.Age. With age, the likelihood of atherosclerosis, hypertension and heart soars error flaps due to vascular changes and abrasion processes.Gender. Men have diseases in General are at a higher risk for early cardiovascular; after Menopause, the risk in women approaches that of men.3. Other important factorsSleep disorders. Obstructive sleep apnea with hypertension, arrhythmic heart rhythm disorders and increased strain on the heart hand-in-hand rule.Infections and systemic inflammation. Chronic infections (e.g., periodontal disease) and autoimmune increase diseases, the inflammatory response in the body, and the atherosclerosis promote.Environmental influences. Fine dust pollution and air pollution are associated with an increased cardiovascular risk.SummaryThe causes of diseases of the cardiovascular system are diverse and often interrelated. While non-modifiable factors such as age and genetics form the basis of, play modifiable life-style factors are the decisive role in prevention. A specific influence of these risk factors through a healthy lifestyle, drug therapy and regular checkups can reduce the individual risk is significant and the quality of life and expectancy significantly improve.Would you like me to make a certain section in more detail, or other aspects of complementary?

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